KMID : 1146220200280030186
|
|
Journal of Cardiovascular Imaging 2020 Volume.28 No. 3 p.186 ~ p.198
|
|
Normal Reference Values for Left Atrial Strain and Its Determinants from a Large Korean Multicenter Registry
|
|
Sun Byung-Joo
Park Jae-Hyeong Lee Min-Yeong Choi Jin-Oh Lee Ju-Hee Shin Mi-Seung Kim Mi-Jeong Jung Hae-Ok Park Jeong-Rang Sohn Il-Suk Kim Hyung-Seop Kim Hyung-Kwan Cho Goo-Yeong Park Jin-Sun Shim Chi-Young Shin Sung-Hee Kim Kye-Hun Kim Woo-Shik Park Seung-Woo
|
|
Abstract
|
|
|
BACKGROUND: Left atrial (LA) strain is a novel parameter of LA function. However, its reference value has not been established, and the determining factors for LA strain remain elusive. We aimed to present LA strain with reservoir, conduit, and contractile components and associated parameters in a large-sized group of healthy individuals.
METHODS: The present study was from a prospective multicenter registry in South Korea. Subjects who had no history of cardiovascular disease with adequate images were eligible for inclusion. LA reservoir, conduit, and contractile strains (LASRES, LASCD and LASCT, respectively) were measured. Left ventricular global longitudinal strain (LV GLS) and early and late diastolic strain rates (DSRe and DSRa, respectively) were also evaluated.
RESULTS: Among a total of 324 subjects (mean age: 49 ¡¾ 16 years, 167 females), the mean LASRES, LASCD, and LASCT values were 35.9% ¡¾ 10.6%, 21.9% ¡¾ 9.3%, and 13.9% ¡¾ 3.6%, respectively. Mean LV GLS was -20.4% ¡¾ 2.2%, and mean DSRe and DSRa were 1.6 ¡¾ 0.4 s-1 and 0.8 ¡¾ 0.3 s-1, respectively. With aging, LASRES and LASCD showed significant decreases. Factors showing independent associations with LASRES were age (B = -0.425, p < 0.001), DSRe (B = 4.706, p = 0.001), and LV GLS (B = -1.081, p < 0.001). Age (B = -0.319, p < 0.001), DSRe (B = 4.140, p = 0.002), DSRa (B = -3.409, p = 0.018), and LV GLS (B = -0.783, p < 0.001) showed associations with LASCD. With LASCT, only DSRa showed a correlation (R = 0.277, p < 0.001).
CONCLUSIONS: We presented LA strain in a large-sized group of healthy subjects. Age is a significant determinant of LA function. Associations of LA strain with diastolic strain rates and LV GLS reflect cardiac mechanics.
|
|
KEYWORD
|
|
LA function, LA strain, Speckle-tracking echocardiography
|
|
FullTexts / Linksout information
|
|
|
|
Listed journal information
|
|
|
|